See more in your LC/MS data.

Metablify is an LC/MS platform built on the first principles of physics.

Explore Metablify
  • A Danforth Technology Company spinout · Developed at the Donald Danforth Plant Science Center
  • Metabolomics · Proteomics · Multi-omics
Plant tissueSoilBloodABCDEFGH123456789101112LC/MSBefore mass adjustmentAfter mass adjustment176.101176.103176.106345678m/zlog10(intensity)Retention-time peak with consensus center8.08.28.48.6345678retention time (min)log10(intensity)8.28featureΔ massreplicabilityS/Ngradepeak 10.24512 / 599180×goldpeak 20.10311 / 59922×greenpeak 30.41142 / 5997×yellowpeak 41.8880 / 5993×redfeaturesample 1sample 2sample 3…gradepeak 18.6e79.2e77.9e7…goldpeak 22.6e61.4e63.1e6…greenpeak 34.5e506.1e5…yellowpeak 41.1e509.4e4…red

Plant tissue, soil, blood, or any other sample you want.

The plant extract is loaded into a 96-well plate.

The plate is one of dozens — experiments scale to thousands of samples.

Each well runs through LC/MS, producing millions of data points per file.

Raw data: every file reports the same mass feature at a slightly different mass.

Metablify aligns them into one feature and quantifies it in every file.

Every feature lands in a table, graded by confidence and quality.

Why Metablify

Don’t leave real mass features in the noise.

Legacy WorkflowsMetablify
LEGACY WORKFLOWSMetablify reveals a broader set of real massfeatures across LC/MS datasets.Legacy workflows detect only a subset of realmass features.A subset of signals reported by legacyworkflows as mass features may be noise orartifacts.

The platform

Discovery starts with the right mass features.

Real Mass Features Get Lost in the Noise

Large LC/MS datasets are noisy, complex, and difficult to align across samples. Real mass features can be missed, split, or buried in background signal.

Metablify Amplifies What is Real

Metablify organizes the chaos of large, noisy datasets to extract the signal from the noise and identify mass features other workflows miss.

Get More From Every Experiment

Cleaner, higher-confidence mass-feature data reduces manual review and provides a stronger foundation for downstream metabolomics, proteomics, and discovery.

The Donald Danforth Plant Science Center, with the entrance courtyard and reflecting pools

Origin

Metablify Was Built to Solve Real LC/MS Workflow Problems.

Metablify was developed at the Donald Danforth Plant Science Center to solve large-scale LC/MS challenges beyond the reach of conventional workflows.

Learn More About Metablify

How it works

Getting Started with Metablify is Simple.

Bring us your samples, LC/MS data, or a challenging workflow. We will help define the right path forward.

  1. 01

    Discuss Your Project

    Tell us about your scientific objective, samples, existing data, and desired outputs.

  2. 02

    Define the Right Approach

    Together, we define the right analytical services, platform-development, or collaboration approach.

  3. 03

    Put Metablify to Work

    Metablify processes and analyzes your LC/MS data to generate cleaner, aligned, and quantified mass-feature results.

  4. 04

    Review Results

    Review results with our team and identify next steps and opportunities for further analysis.

Ready to See More in Your LC/MS Data?

Bring us your samples, LC/MS data, or workflow challenge. We will help determine the right path forward.

Discuss Your Project